01 DEPMAP · CELL LINES
Genetic dependencies
Look up CRISPR Chronos Gene Effect by model or lineage, survey pan-cancer patterns, and explore precomputed co-dependency and cross-platform comparisons.
depmap_model_gene_effect
DEPMAP PUBLIC 26Q1 MCP
Cancer dependency
evidence for
research agents.
Pharmaco brings precomputed cancer cell-line evidence and TCGA cohort summaries into MCP workflows. Ask about a gene, lineage, or compound and retrieve results with release, coverage, and provenance.
Connect to Pharmaco01 / EVIDENCE
What you can query
02 DEPMAP · CELL LINES
Drug response
Retrieve retained drug sensitivity associations and check whether a target has an eligible, validated expression biomarker model.
depmap_drug_evidence
03 TCGA · PATIENT COHORTS
Expression & survival
Inspect precomputed expression and survival associations by TCGA project. Cohort summaries retain their own metrics and coverage.
tcga_gene_expression_survival
Keep TCGA cohort associations and DepMap cell-line results separate. Use the returned evidence_id and release when citing results, and read coverage states before interpreting missing rows.
02 / ACCESS
Connect an MCP client
External access is being configured. Once enabled, use a Streamable HTTP client with support for request headers and credentials issued by the project team.
PLANNED ENDPOINT
https://pharmaco-mcp.gzdlab.com/mcp
Start with depmap_capabilities and depmap_data_coverage to discover the queries and evidence available for your question.